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Tenvir EM (Emtricitabine & Tenofovir) 30 Tablets

Tenvir EM (Emtricitabine & Tenofovir) 30 Tabletsx3 3 $55.1 $165.30
Tenvir EM (Emtricitabine & Tenofovir) 30 Tabletsx6 6 $49.8 $298.80
Tenvir EM (Emtricitabine & Tenofovir) 30 Tabletsx10 10 $46.8 $468.00

Product Information

Tenvir EM is a combination drug consisting of two active ingredients, 200mg of Emtricitabine and 300mg of Tenofovir disoproxil fumarate which are both antiviral drugs. This combination drug is prescribed to treat HIV infection and to prevent of getting HIV infection.

As treatment for HIV infection, this medication is used with other HIV medications to prevent the virus called HIV in spreading or multiplying in the body. This virus is popularly known to cause Acquired Immunodeficiency Syndrome or AIDS. The Human Immunodeficiency Virus (HIV) damages the immune system by specifically attacking the immune cells CD4+, cells which helps fight infection. When these cells are damaged, it can lead to life-threatening infections. Too much damaged CD4+ cells can result to AIDS. As Tenvir EM prevents the multiplication and spread of HIV, it keeps the virus down to low levels to help increase CD4+ cells, help the body recover and reduce the progression of the disease.

As prevention of getting HIV infection, this medication is used with safe sex practices. It is used for adults who are at high risk of getting HIV. Those who are at high risk include male-female or male-male sex partners where one partner is HIV infected, and also where males or females have sex with IV drug users at risk of contracting HIV.

Tenvir EM, containing two antiretroviral drugs emtricitabine and tenofovir disoproxil fumarate is effective against HIV by inhibiting the enzymes needed by the virus to replicate. Retroviruses like HIV convert RNA to DNA which becomes integrated with the DNA of infected immune cells necessary for replication. The two active drugs block the enzyme needed for transcribing viral RNA to DNA, preventing the integration of the virus into the DNA of infected immune cells thus inhibiting the replication of HIV and reduces amount of virus.

Tenvir EM slows down HIV replication but does not kill the virus, nor cure HIV infection or AIDS. This medication does not prevent the transmission of infection to others.


Tenvir EM is manufactured by Cipla Pharmaceuticals


Tenvir EM is contraindicated to patients who are allergic to any of its ingredients. It is also contraindicated to patients taking the following:

  • Other medicines containing emtricitabine, tenofovir alafenamide, tenofovir disoproxil fumarate, lamivudine, adefovir, or other antiretroviral drugs that have the same mechanism as Tenvir EM
  • Medicines that interact with Tenvir EM

Tenvir EM must not be taken to reduce risk of HIV infection if a patient is HIV-positive, has been exposed to HIV within the past month, has symptoms such as fever, body aches, headache, sore throat, vomiting, diarrhea, tiredness, night sweats, swollen lymph nodes.

Side effects

Warnings and Precautions

To make sure that Tenvir EM is safe to take, a patient must inform a physician of all health problems including:

  • kidney problems
  • bone problems
  • liver problems
  • hepatitis B infection

Lactic acidosis is a fatal condition that has rarely been reported with use of Tenvir EM. It is caused by a build-up of excess lactic acid due to liver damage. Symptoms may show within a few months of treatment such as nausea, vomiting, abdominal pain, breathing difficulty, appetite loss, weight loss, motor weakness, dizziness, fast or uneven heart rate, feeling weak or tired. Women, people overweight, people with liver disease and people who took HIV medications for a long time are more likely to develop lactic acidosis.

A patient must also inform a physician of all medications being taken; prescription or over-the-counter, vitamins and herbal supplements because of possible interaction with Tenvir EM, such as:

  • other HIV medications
  • pain or arthritis medications
  • hepatitis C medications
  • chemotherapy
  • injected antibiotics
  • injectable osteoporosis medications
  • bowel disorder medications
  • medications that prevent organ transplant rejection

This is not a complete list of drug interactions.

It is not known if Tenvir EM can harm an unborn baby. Pregnant women or women planning to get pregnant must talk to a healthcare provider.

Breastfeeding must be avoided when taking this medication. The drug can be passed into breastmilk. HIV can also be passed to the nursing infant via breastmilk.

Avoid having unprotected sex, avoid sharing razors, toothbrushes, drug or medicine needles, etc. Taking the medication will not prevent passing HIV infection to others.

Caution is advised when driving or performing unsafe tasks because of the dizziness Tenvir EM may cause.

Tenvir EM and Alcohol

Tenvir EM may cause dizziness and this side effect may become worse if the medication is taken with alcohol.


A patient must take Tenvir EM exactly as prescribed by the physician. The usual adult dose of Tenvir EM is 1 tablet orally once a day. This medication must be swallowed whole with a glass of water and may be taken with or without food as food does not affect the efficacy of the drug. It is best to take the tablet at same times each day to help the patient remember when to take it. If a dose is forgotten, it must be taken as soon as remembered that day. A patient must never increase the prescribed dose. It is however crucial not to miss any dose of Tenvir EM to prevent the risk of increasing the amount of virus in the blood or developing resistance to the medication, making it hard to treat.

For treating HIV infection, the patient must first be tested before using this medication. This antiretroviral drug combination is used with other antiretroviral medicines to help treat HIV infection.

For reducing risk or preventing HIV infection, a patient must first be tested and must be confirmed HIV-negative before starting to take this medication. A patient must also continue to practice safer sex while taking Tenvir EM to reduce the risk of getting HIV. A dose must never be missed, otherwise, it will increase the risk of getting HIV. To further reduce the risk of getting infected, a patient must maintain being HIV-negative and must do the following:

  • • Know self and partner’s HIV status
  • • Get tested for HIV every 3 months
  • • Report exposure to HIV to healthcare providers suspected

Tenvir EM is approved for treating HIV infection in patients weighing at least 35kg.

Side effects

Common side effects of Tenvir EM may include headache, dizziness, feeling tired, feeling depressed, stomach pain, rash, weight loss, sleep problems, strange dreams

Serious side effects may include:

  • • Kidney problems with symptoms of painful or difficult urination, little or no urination, feeling tired, shortness of breath, swelling of ankles or feet. If a patient develops kidney problems, a physician may reduce the dose or discontinue therapy.
  • • Liver problems with symptoms of nausea, upper stomach pain, unusual tiredness, appetite loss, dark urine, clay colored stools, jaundice, swelling of midsection.
  • • Bone problems including bone pain, softening or thinning of bones leading to fractures.
  • • Changes in body fat
  • • Changes in immune system – may increase risk of other infections or autoimmune disorders. Symptoms may include the following:
    • Signs of new infection – fever, swollen glands, mouth sores, diarrhea, weight loss, stomach pain, night sweats
    • Chest pain, dry cough, wheezing, shortness of breath
    • Cold sores, sores in the anal or genital area
    • Swelling in neck or throat, menstrual changes, loss of interest in sex, impotence
    • Trouble swallowing or speaking, loss of bladder or bowel control, severe low back pain
    • Rapid heart rate, anxiousness, irritability, balance and eye movement problems

Refer to drug leaflet or consult a healthcare provider for more information on Tenvir EM side effects.

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