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Isentress 400 (Raltegravir)
Qty Price per Unit Price
Isentress 400 (raltegravir) x 3 $129.00 $387.00
Isentress 400 (raltegravir) x 5 $119.00 $595.00


Isentress 400mg (30/bottle)

Isentress 400mg (raltegravir) belongs to a group of antiretroviral drugs that prevent human immunodeficiency virus (HIV) from multiplying in your body. Isentress 400mg is a HIV medication used to treat HIV, the virus that can cause the acquired immunodeficiency syndrome (AIDS). Isentress is not a cure for HIV or AIDS. It is for use in adults and children who weigh at least 4.4 pounds (2 kilograms).


The usual dose of isentress for adolescents and adults is one 400 mg tablet, taken by mouth, 2 times daily or two 600 mg tablets taken once daily. The dose of chewable tablets for children more than 2 years old but less than 12 years of age is based on the child's body weight. Do not switch between the 400 mg tablets, 600 mg tablets, or the chewable tablets without checking with your doctor first.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Side effect

Headache, nausea, and trouble sleeping, Blood in the urine, burning or stinging of the skin

dark urine, decreased frequency or amount of urine, fast heartbeat, fever, general tiredness and weakness, hoarseness, increased thirst, irritation, joint pain, stiffness, or swelling, light-colored stools, loss of appetite, lower back or side pain, nausea, pain in the groin or genitals, painful blisters on the trunk of the body, painful cold sores or blisters on the lips, nose, eyes, or genitals, rash, hives or itching, redness of the skin, sharp bark pain just below the ribs, swelling of the eyelids, face, lips, hands, lower legs, or feet, tightness in the chest, troubled breathing or swallowing, unusual tiredness or weakness, upper right stomach pain, vomiting, weight gain, yellow eyes and skin,  may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

As your immune system gets stronger, it can begin to fight off infections you already had, possibly causing disease symptoms to come back. You could also have symptoms if your immune system becomes overactive. This reaction may happen at any time (soon after starting HIV treatment or many months later). Get medical help right away if you have any serious symptoms, including: unexplained weight loss, severe tiredness, muscle aches/ weakness that doesn't go away, headaches that are severe or don't go away, joint pain, numbness/tingling of the hands/feet/arms/legs, vision changes, signs of infection (such as fever, chills, swollen lymph nodes, trouble breathing, cough, non-healing skin sores), signs of an overactive thyroid (such as irritability, nervousness, heat intolerance, fast/pounding/irregular heartbeat, bulging eyes, unusual growth in the neck/thyroid known as a goiter), signs of a certain nerve problem known as Guillain -Barre syndrome (such as trouble breathing/swallowing/moving your eyes, drooping face ,paralysis, trouble speaking).


Hypersensitivity syndrome: A severe allergic reaction called hypersensitivity syndrome has occurred for some people with the use of isentress. This reaction involves a number of organs in the body and may be fatal if not treated quickly. Stop taking the medication and get immediate medical attention if you have symptoms of a severe allergic reaction, including fever, swollen glands, yellowing of the skin or eyes, or flu-like symptoms with skin rash or blistering.

Immune reconstitution syndrome: This medication may cause immune reconstitution syndrome, where signs and symptoms of inflammation from previous infections appear. These symptoms occur soon after starting anti-HIV medication and can vary. They are thought to occur as a result of the immune system improving and being able to fight infections (e.g., pneumonia, herpes, or tuberculosis) that have been present without symptoms. Report any new symptoms to your doctor immediately.

Muscle pain: Occasionally, isentress causes breakdown of muscle tissues, which can be fatal. Report any symptoms of severe, unexplained muscle pain to your doctor as soon as possible.

Phenylketonuria (PKU): People with phenylketonuria, a disorder where the body cannot break down the amino acid phenylalanine, should not use the chewable tablets. The artificial sweetener in the chewable tablets contains phenylalanine and will be harmful to someone with PKU.

Skin reactions: Isentress may cause skin rash or itchiness with or without a rash. On rare occasions, people taking isentress experience a severe skin reaction that can be life-threatening. If you experience a rash that gets worse, or develops into blisters or sores on the lips or eyes, or covers a large area of the body, contact your doctor immediately.

Pregnancy: There are no studies evaluating the use of this medication by pregnant women. This medication is not recommended during pregnancy. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: It is not known if this medication passes into breast milk. However, breast-feeding is not recommended for HIV-positive women since the virus can be passed to the baby through breast milk.

Children: The safety and effectiveness of using this medication have not been established for children less than 2 years old.



Additional Information

Manufacturer MSD