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Tenvir FM (Tenofovir Disoproxil fumerate IP) 30 Tablets

$59.90
Qty Price per Unit Price
Tenvir Fm (tenofovir Disoproxil Fumerate Ip) 30 Tablets x 3 $55.10 $165.30
Tenvir Fm (tenofovir Disoproxil Fumerate Ip) 30 Tablets x 6 $49.80 $298.80
Tenvir Fm (tenofovir Disoproxil Fumerate Ip) 30 Tablets x 10 $46.80 $468.00

Details

Product Information

Tenvir FM is an antiviral prescription medication that contains 300mg of Tenofovir Disoproxil Fumarate. Tenvir FM is used in combination with other antiretroviral drugs to treat HIV-1 infection in adults and children aged 2 years and above. This drug belongs to the group of HIV medications called nucleoside reverse transcriptase inhibitors (NRTIs). This group works by blocking the HIV enzyme reverse transcriptase which then prevents the Human Immunodeficiency Virus (HIV) from multiplying, reducing the amount of the virus in the body.

HIV medications are usually taken in combination with other HIV medicines to help infected people live healthier and longer lives. However, HIV medications can not cure HIV infection or AIDS and patients may still experience other infections or diseases associated with HIV infection.

Tenvir FM is also effective in treating HBV infection in adults and children aged 12 years and older.

Manufacturer

Tenvir FM is manufactured by Cipla Pharmaceuticals

Dosage

A patient must take Tenvir FM exactly as prescribed by the physician. The usual dose of Tenvir FM for adults and pediatrics aged 12 years and older for the treatment of HIV is 300mg orally once a day. For patients 2 years to less than 12 years of age, the recommended dose is 8mg per kilogram of body weight (up to 300mg maximum) once daily. A tablet of Tenvir FM must be swallowed whole with a glass of water and may be taken with or without food as food does not affect the efficacy of the drug. It is important that a patient remains under the care of a healthcare provider while taking this medication.

Intake of Tenvir FM must not be discontinued without the advice of a physician. It is best to take the tablet at same times each day to help the patient remember when to take it. If a dose is forgotten, it must be taken as soon as remembered that day but the missed dose must be skipped if it’s almost time for the next dose; the next regular dose should then be taken at the next dosing schedule. A patient must never increase the prescribed dose. It is however crucial not to miss any dose of Tenvir FM to prevent the risk of increasing the amount of virus in the blood or developing resistance to the medication, making it hard to treat.

For treating HIV infection, the patient must first be tested before using this medication. For reducing risk or preventing HIV infection, a patient must first be tested and must be confirmed HIV-negative before starting to take this medication. A patient must also continue to practice safer sex while taking Tenvir FM to reduce the risk of getting HIV. A dose must never be missed, otherwise, it will increase the risk of getting HIV. To further reduce the risk of getting infected, a patient must maintain being HIV-negative and must do the following:

  • Know self and partner’s HIV status
  • Get tested for HIV every 3 months
  • Report exposure to HIV to healthcare providers

Contraindications

Tenvir FM is contraindicated to patients who are allergic to any of its ingredients. It is also contraindicated to patients taking other medicines containing tenofovir alafenamide, tenofovir disoproxil fumarate, lamivudine, adefovir, or other antiretroviral drugs that have the same mechanism as Tenvir FM, and medicines that interact with Tenvir FM. This medication is also contraindicated to lactating women because this drug can be passed in breast milk.

Tenvir FM must not be taken to reduce risk of HIV infection if a patient is HIV-positive, has been exposed to HIV within the past month, has symptoms such as fever, body aches, headache, sore throat, vomiting, diarrhea, tiredness, night sweats, swollen lymph nodes.

Side effects

Most of the side effects of Tenvir FM are manageable such as headache, nausea, feeling tired, weakness, feeling depressed, stomach pain, diarrhea, or rash. However, Tenvir FM may also cause serious side effects. Serious and potentially life-threatening side effects may include:

  • Severe liver problems with symptoms of nausea, upper stomach pain, unusual tiredness, appetite loss, dark urine, clay colored stools, jaundice, swelling of midsection, and yellowing of skin or whites of the eyes.
  • Lactic acidosis or too much lactic acid in the blood. Symptoms may include weakness, more tired than usual, unusual muscle pain, shortness of breath, fast breathing, stomach pain with vomiting and nausea, dizziness or lightheadedness, fast or abnormal heartbeat, cold or blue hands and feet.

Other side effects include:

  • New or worsening kidney problems including kidney failure. Symptoms may include painful or difficult urination, little or no urination, feeling tired, shortness of breath, swelling of ankles or feet. If a patient develops kidney problems, a physician may reduce the dose or discontinue therapy.
  • Bone problems including bone pain, softening or thinning of bones leading to fractures.
  • Changes in body fat – gain or loss of fat or redistribution that may cause cushingoid appearance
  • Changes in immune system or Immune Reconstitution Syndrome. This may occur when the immune system recovers after treatment with HIV medications. The immune system may get stronger to fight off previously hidden infections. Any new symptoms that may arise must be reported to healthcare providers.

Tenvir FM may also increase the risk of new infections or autoimmune disorders by changing the way the immune system works. Symptoms may develop weeks or months after start of treatment. Symptoms may include:

  • Fever, swollen glands, mouth sores, diarrhea, stomach pain, weight loss, night sweats as signs of new infection
  • Dry cough, wheezing, shortness of breath, chest pain
  • Cold sores, sores on the genital or anal area
  • Trouble swallowing or speaking, severe low back pain, loss of bladder or bowel control
  • Swelling of neck or throat (enlarged thyroid), menstrual changes, impotence, loss of libido
  • Rapid heart rate, anciousness, irritability, balance problems, eye movement problem

Some patients may develop an allergic reaction to Tenvir FM and symptoms include hives, breathing difficulty, and swelling of face, lips, tongue, or throat.

Refer to drug leaflet or consult a healthcare provider for more information on Tenvir FM side effects.

Warnings and Precautions

Before taking Tenvir FM, a patient must first inform the healthcare provider if any of the following applies:

  • Allergy to the active ingredient or any of the ingredients of Tenvir FM
  • Have liver problems, as well as HBV infection
  • Have kidney problems
  • Have bone problems
  • Have other medical conditions
  • If breastfeeding
  • If pregnant or planning to get pregnant. It is not known if Tenvir FM can harm an unborn baby. The medication should only be used if clearly needed. The risks should be discussed with a healthcare provider

A patient must also inform a physician of all medications being taken; prescription or over-the-counter, vitamins and herbal supplements because of possible interaction with Tenvir FM, such as:

  • other HIV medications
  • hormone-based birth control
  • pain or arthritis medications
  • hepatitis C medications
  • chemotherapy
  • injected antibiotics
  • injectable osteoporosis medications
  • bowel disorder medications
  • medications that prevent organ transplant rejection

This is not a complete list of drug interactions. Refer to drug leaflet for more information.

Taking the medication will not prevent passing HIV infection to others. Patients must avoid the following to prevent the spread of infection:

  • Breastfeeding must be avoided. Mothers with HIV infection can pass it to the nursing infant via breastmilk. The drug can be passed into breastmilk. It is now known if the drug can harm the baby.
  • Avoid having unprotected sex. Use of latex or polyurethane condoms is advisable to reduce the chance of sexual contact with vaginal secretions, semen, or blood.
  • Avoid sharing personal items that can have blood or body fluids on them such as toothbrushes or razors.
  • Avoid sharing needles or other injection equipment.

Tenvir EM and Alcohol

Drinking alcohol must be avoided for it may increase the risk of liver damage.