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Tamofar 20mg (Tamoxifen)

$1.50
Qty Price per Unit Saving Price
Tamofar 20mg (tamoxifen) x 30 $0.90 $45.00 $27.00
Tamofar 20mg (tamoxifen) x 60 $0.75 $63.00 $45.00
Tamofar 20mg (tamoxifen) x 90 $0.65 $90.00 $58.50
Tamofar 20mg (tamoxifen) x 180 $0.45 $211.50 $81.00
Tamofar 20mg (tamoxifen) x 360 $0.35 $459.00 $126.00

Details

Product Information

 

Tamofar 20 contains 20mg of the active ingredient Tamoxifen citrate. Tamoxifen belongs to a class of drugs called selective estrogen receptor modulators (SERMs) which possess both estrogenic and anti-estrogenic effects.

 

Tamoxifen is prescribed for the following:

  • As an adjuvant therapy for lymph node negative or positive breast cancer in both women and men.

Tamoxifen is more likely effective in cancers with positive estrogen and progesterone receptors. This drug reduces the risk of having breast cancer on the opposite breast.

  • Treatment of metastatic breast cancer in women and men.
  • Treatment of ductal carcinoma in situ in women, following surgery and radiation therapy.

Tamoxifen may reduce the risk of invasive breast cancer.

  • As a preventive therapy to reduce the risk of developing breast cancer for women who are at a high risk due to age and family or personal medical history.

 

Tamoxifen works by binding to estrogen receptors in the cancer cells and blocks the estrogen’s proliferative effects on breast tissues, stopping the growth of breast tumors that require estrogen.

 

Manufacturer

 

Tamofar 20 is manufactured by Shree Venkatesh International

 

Dosage

 

A physician will determine the right dosage per patient as it will depend on the condition to be treated, the patient’s response to the medication, other health conditions and medications.  A physician will also determine the duration of treatment. It is important that a physician’s dosage instructions be strictly followed.  

 

Tamofar tablets must be taken orally, swallowed whole with a glassful of water. It may be taken with or without food. A dose of Tamofar higher than 20mg are usually divided into half and taken twice daily, in the morning and evening.  

 

The usual adult doses for breast cancer are as follows:

In treating metastatic breast cancer in women and men

  • 20mg to 40mg daily

 

In treating Ductal Carcinoma in Situ in women following breast surgery and radiation

  • 20mg once a day for 5 years

 

In reducing the risk of breast cancer in high-risk women

  • 20mg once a day for 5 years

 

As an adjuvant therapy for breast cancer

  • 10mg twice or thrice daily for 5 years

 

If Tamofar is to be used to reduce the risk of breast cancer, the first dose may need to be taken while having menstrual period.

 

This drug is best taken regularly, around the same time each day and strictly follow the physician’s instructions to get optimum benefit from it.

 

Regular physical exams, self-examination and mammograms are recommended while taking this medication. Women will need regular gynecologic examinations before and during Tamoxifen therapy. Periodic blood work may also be required by a physician to monitor CBC and other organ functions like kidneys and liver.

 

Take a missed dose as soon as remembered. Skip the missed dose if it’s almost time for the next dose. Never double the dose just to make up for the missed one.

 

Contraindications

 

This medication is contraindicated to patients with known allergy to Tamofar’s active ingredient Tamoxifen, and all its inactive ingredients.

 

This medication is contraindicated to pregnant women as the drug may harm an unborn baby. Avoid getting pregnant while on Tamoxifen therapy. Using of non-hormonal birth control such as condom or diaphragm is recommended while taking this medication and at least 2 months after drug therapy.

 

Tamofar is also contraindicated to women taking coumarin-type anticoagulant therapy such as Warfarin and in women with a history of blood clots in veins or lungs.

 

Side effects

 

Side effect experience varies per patient. Some patients will experience side effects, others may not. Some side effects are reversible and may disappear after some time.

 

The side effects of Tamofar such as nausea, headache, hot flashes, leg cramps, hair thinning, weight loss, vaginal discharge, and numbing or tingling of skin may occur in more than 30% of patients taking the drug. Loss of sexual interest and impotence in men has been reported upon discontinuation of therapy.

 

A physician must be notified of any of the following serious side effects:

  • vision changes
  • eye pain
  • unusual bruising or bleeding
  • fever
  • mental or mood changes
  • changes in menstrual period
  • unusual vaginal discharge or bleeding
  • pain or pressure in the pelvic area
  • new breast lump
  • signs of high calcium blood levels – vomiting, constipation, increased thirst and urination, muscle weakness, unusual tiredness, bone pain, confusion
  • signs of liver problems – upper stomach pain, appetite loss, dark urine, clay-colored stools, jaundice (yellowing of eyes or skin)

 

Tamoxifen may rarely cause serious side effects like blood clots in veins and lungs. Seek medical help if sudden chest pain and shortness of breath occur or if one leg swells, turns red and is painful or warm to the touch.

 

Tamoxifen may also cause a development of other cancers such as uterine cancer. Abnormal vaginal bleeding must be reported to a physician. Regular pap smears and gynecological examinations are recommended.

 

If this drug is taken for the treatment of metastasized breast cancer, increased bone/cancer pain or disease flare-up can occur. This however may be a sign of a good tumor response to the medication. Notify a physician of these occurrences.

 

Stop the medication and urgent medical attention is needed if a serious allergic reaction to the drug occurs. Symptoms include rash, itching, swelling of face, tongue and throat, breathing difficulty and severe dizziness.

 

Consult a physician for a complete information on Tamofar side effects.

 

Warnings and Precautions

 

Before taking Tamofar, it is important to know if the drug is safe for use. Inform a physician of any of the following in order to know if the drug is safe to take:

  • history of stroke or blood clot
  • liver disease
  • high cholesterol or triglycerides
  • history of cataracts
  • diabetes
  • high blood pressure
  • limited or inability to walk
  • on a chemotherapy or radiation therapy
  • pregnant or planning to get pregnant

 

Tamoxifen may interact with other medications, vitamins, and herbal supplements. This drug must not be used concomitantly with anastrozole and letrozole as it can cause serious interactions. Inform a physician of any of the following medications being taken or planning to take:

  • aminoglutethimide
  • bromocriptine
  • cancer chemotherapy medication like cyclophosphamide
  • medroxyprogesterone
  • phenobarbital
  • rifamycins
  • coumarin-type anticoagulants
  • estrogens
  • hormonal forms of birth control

 

Cimetidine and SSRI antidepressants are some of the drugs that can affect the elimination of Tamoxifen from the body, hence affecting how the drug works.

 

This medication may interfere with certain laboratory tests including thyroid tests causing a false test result.

 

Breastfeeding while taking this medication is not recommended for it is unknown whether Tamoxifen can harm a nursing baby or if drug is excreted in breast milk. However, this drug can slow down production of breast milk.

 

Tamofar and Alcohol


Concomitant use of alcohol and Tamoxifen is not recommended. Drinking alcohol while taking Tamoxifen (Tamofar) may increase the risk of side effects such as dizziness, drowsiness and increased risk of heart attack and stroke.